Chicken Heat Shock Protein 90kDa Alpha A1,HSP90aA1 ELISA KIT

SKU: E0031Ch

Size:96 Tests-1 Kit

Background:Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity which is essential for its chaperone activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a range of client protein classes via its interaction with various co-chaperone proteins or complexes, that act as adapters, simultaneously able to interact with the specific client and the central chaperone itself. Recruitment of ATP and co-chaperone followed by client protein forms a functional chaperone. After the completion of the chaperoning process, properly folded client protein and co-chaperone leave HSP90 in an ADP-bound partially open conformation and finally, ADP is released from Hsp90 which acquires an open conformation for the next cycle. {ECO:0000250|UniProtKB:P07900}.

Research_area:

Applications:ELISA

Target_protein:HSP90AA1

Reactivity:Chicken

Assay type:Sandwich

Sensitivity:0.015ng/ml

Detection range:0.05-20ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Heat Shock Protein 90kDa Alpha A1

Species:Chicken

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P11501

MASS(Da):84059

GeneID:423463

Synonyms:HSP90AA1 HSPCA

Gene names:HSP90AA1

Standard solution:24ng/ml