Chicken Dickkopf-3,DKK3 ELISA KIT

SKU: E0075Ch

Size:96 Tests-1 Kit

Background:Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease (By similarity). {ECO:0000250}.

Research_area:

Applications:ELISA

Target_protein:DKK3

Reactivity:Chicken

Assay type:Sandwich

Sensitivity:0.098ng/ml

Detection range:0.2-60ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Dickkopf-3

Species:Chicken

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q90839

MASS(Da):39209

GeneID:396023

Synonyms:DKK3

Gene names:DKK3

Standard solution:64ng/ml