CDX2 Mouse mAb

SKU: EM1057

Size: 100μL

Source:Mouse

Applications:WB, IHC

Reactivity:Human, Rat, Mouse

Dilution:WB 1:1,000 IHC 1:200

Immunogen:Synthetic Peptide

Storage_stability:PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Clonality:Monoclonal

Isotype:IgG1

Concentration:1mg/mL

Observed_band(KD):42kDa

Human_gene_id:1045

Human_swiss_prot_no:Q99626

Subcellular_location:Nucleus

Other_name:Caudal Type Homeobox Transcription Factor 2 ;CDX3; Homeobox Protein CDX-2

Background:CDX2 is a caudal type homeobox gene that encodes an intestine-specific transcription factor that is expressed early in intestinal development and may be involved in the regulation of proliferation and differentiation of intestinal epithelial cells. It is expressed in the nuclei of epithelial cells throughout the intestine, from duodenum to rectum. The CDX2 protein is expressed in primary and metastatic colorectal carcinomas and has also been demonstrated in the intestinal metaplasia of the stomach and intestinal-type gastric cancer, while it is not expressed in the normal gastric mucosa. Studies have shown that CDX2 is superior marker compared to CK20.