CDKN1B Polyclonal Antibody

SKU: E-AB-52142

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: CDKN1B

Target Synonym: AA408329;AI843786;Cdki1b;CDKN 1B;CDKN 4;CDKN1B;CDKN4;CDN1B;Cyclin Dependent Kinase Inhibitor 1B;Cyclin dependent kinase inhibitor p27;Cyclin-dependent kinase inhibitor 1B (p27;Kip1);Cyclin-dependent kinase inhibitor 1B;Cyclin-dependent kinase inhibitor p27;Cyclin-dependent kinase inhibitor p27 Kip1;KIP 1;KIP1;MEN1B;MEN4;OTTHUMP00000195098;OTTHUMP00000195099;p27;p27 Kip1;P27-like cyclin-dependent kinase inhibitor;p27Kip1

Research Areas: Cancer;Cell Biology;Epigenetics and Nuclear Signaling

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human;Mouse

Application: IHC

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: P46527

Accession:

Background: This gene encodes a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state. Mutations in this gene are associated with multiple endocrine neoplasia type IV (MEN4).

Concentration: 1.32 mg/mL

Immunogen: Fusion protein of human CDKN1B

Buffer: PBS with 0.05% NaN3 and 40% Glycerol,pH7.4

Purification method: Antigen affinity purification

Dilution: IHC 1:50-1:300

Calculated MW:

ObservedMW: