CDH23 Antibody - Cat. #: CSB-PA207598

SKU: CSB-PA207598

Size :100ul

Clone Number:

Aliases:CDH23 antibody; KIAA1774 antibody; KIAA1812 antibody; UNQ1894/PRO4340Cadherin-23 antibody; Otocadherin antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q9H251

Immunogen:Synthesized peptide derived from internal of Human CDH23.

Raised in:Rabbit

Species Reactivity:Human, Mouse

Tested Applications:ELISA, IF; IF:1:100-1:500

Background:Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells. CDH23 is required for establishing and/or maintaining the proper organization of the stereocilia bundle of hair cells in the cochlea and the vestibule during late embryonic/early postnatal development. It is part of the functional network formed by USH1C, USH1G, CDH23 and MYO7A that mediates mechanotransduction in cochlear hair cells. Required for normal hearing.

Bolz H., Nat. Genet. 27:108-112(2001).
Clark H.F., Genome Res. 13:2265-2270(2003).
Bork J.M., Am. J. Hum. Genet. 68:26-37(2001).

Clonality:Polyclonal

Isotype:IgG

Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:CDH23

Research Areas:Neuroscience;Signal transduction