CDC42BPA Antibody - Cat. #: CSB-PA019608

SKU: CSB-PA019608

Size :100ul

Clone Number:

Aliases:A930014J19Rik antibody; CDC42 binding protein kinase alpha (DMPK like) antibody; CDC42 binding protein kinase alpha antibody; CDC42 binding protein kinase alpha dmpk like antibody; CDC42 binding protein kinase beta antibody; CDC42-binding protein kinase alpha antibody; CDC42BPA antibody; DKFZp686L1738 antibody; DKFZp686P1738 antibody; DMPK like antibody; DMPK-like alpha antibody; FLJ23347 antibody; KIAA0451 antibody; MGC189823 antibody; MRCK alpha antibody; mrck antibody; mrcka antibody; MRCKA_HUMAN antibody; Myotonic dystrophy kinase related CDC42 binding protein kinase alpha antibody; Myotonic dystrophy kinase-related CDC42-binding kinase alpha antibody; Myotonic dystrophy protein kinase-like alpha antibody; OTTHUMP00000035727 antibody; OTTHUMP00000035728 antibody; OTTHUMP00000035729 antibody; OTTHUMP00000035730 antibody; pk428 antibody; RP5-1087E8.4 antibody; Ser thr protein kinase PK428 antibody; Ser thr protein kinase related to the myotonic dystrophy protein kinase antibody; Serine/threonine protein kinase MRCK alpha antibody; Serine/threonine-protein kinase MRCK alpha antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q5VT25

Immunogen:Synthesized peptide derived from Internal of Human MRCKa.

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, WB, IHC, IF; WB:1:500-1:3000, IHC:1:50-1:200, IF:1:100-1:200

Background:Serine/threonine-protein kinase which is an important downstream effector of CDC42 and plays a role in the regulation of cytoskeleton reorganization and cell migration. Regulates actin cytoskeletal reorganization via phosphorylation of PPP1R12C and MYL9/MLC2. In concert with MYO18A and LURAP1, is involved in modulating lamellar actomyosin retrograde flow that is crucial to cell protrusion and migration. Phosphorylates: PPP1R12A, LIMK1 and LIMK2. May play a role in TFRC-mediated iron uptake.

Wilkinson S., Nat. Cell Biol. 7:255-261(2005).
Totoki Y., Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
Bechtel S., BMC Genomics 8:399-399(2007).

Clonality:Polyclonal

Isotype:IgG

Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:CDC42BPA

Research Areas:Signal transduction