CD338 Monoclonal Antibody

SKU: BT-MCA4425

Size:100μL

Background:The membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue. Multiple transcript variants encoding different isoforms have been found for this gene.

Research_area:Others

Target_protein:CD338

applications:WB, IHC, ICC, FCM

Reactivity:

Clonality:Monoclonal

Clone ID:4H3C10

Host:Mouse

Isotype:Mouse IgG2b

Gene Symbol/ Name:CD338

Immunogen:Purified recombinant fragment of human CD338 (AA: extra mix) expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Purified antibody in PBS with 0.05% sodium azide

Concentration:

Molecular weight(Da):75kDa

UniProt accession:Q9UNQ0

Synonyms:MRX, MXR, ABCP, BCRP, BMDP, MXR1, ABC15, BCRP1, ABCG2, GOUT1, MXR-1, CDw338, UAQTL1, EST157481

GeneID:9429