CD289 Monoclonal Antibody

SKU: BT-MCA3893

Size:100μL

Background:The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is preferentially expressed in immune cell rich tissues, such as spleen, lymph node, bone marrow and peripheral blood leukocytes. Studies in mice and human indicate that this receptor mediates cellular response to unmethylated CpG dinucleotides in bacterial DNA to mount an innate immune response.

Research_area:Others

Target_protein:CD289

applications:FCM

Reactivity:Human

Clonality:Monoclonal

Clone ID:5B10E8

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:CD289

Immunogen:Purified recombinant fragment of human CD289 (AA: extra 26-193) expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Purified antibody in PBS with 0.05% sodium azide

Concentration:

Molecular weight(Da):116kDa

UniProt accession:Q9NR96

Synonyms:TLR9

GeneID:54106