CD19 Monoclonal Antibody

SKU: AN200122P

Size::20μL

Storage:This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Monoclonal Antibodies

Abbreviation:CD19

Target Synonym:CVID;B-lymphocyteantigenCD;B-lymphocyte antigen CD;T-cellsurfaceantigenLeu;Differentiation antigen CD;T-cell surface antigen Leu;B-lymphocytesurfaceantigenB;B-lymphocyte surface antigen B;B4;CVID3;CD19;B-lymphocyteantigenCD19;B-lymphocytesurfaceantigenB4;T-cellsurfaceantigenLeu-12;B-lymphocyte antigen CD19;B-lymphocyte surface antigen B4;Differentiation antigen CD19;T-cell surface antigen Leu-12;B4;CVID3;CD19;CD19 molecule

Research Areas:Immunology;Stem Cells

Conjugation:Unconjugated

Host:Mouse

Species reactivity:Human

Application:WB

Isotype:IgG1

Clonality:Monoclonal

Clone NO.:5F10

UNIProt ID:P15391

Accession:

Background:CD19 protein is a 95 kDa transmembrane glycoprotein that plays a central role in B cell activation and humoral immune responses . CD19 is expressed throughout B cell development from pre-B cells through mature B cells, and it is commonly used as a B cell lineage marker . It is required for the responsiveness of mature B cell to antigen stimulation, germinal center development, and antibody affinity maturation . The CD19 protein associates with the B cell antigen receptor (BCR), CD81, CD38, CD21, CD22, and IFITM1/CD225/Leu13. These associations enable CD19 to amplify B cell signaling and reduce the threshold for antigen stimulation through the BCR.

Concentration:1 mg/mL

Immunogen:Recombinant Human CD19 Protein

Buffer:0.2 μm filtered solution in PBS

Purification method:Protein A

Dilution:WB 1:500-1:2000;

Calculated MW:61 kDa

ObservedMW:61 kDa