CD174 Monoclonal Antibody

SKU: BT-MCA4408

Size:100μL

Background:The Lewis histo-blood group system comprises a set of fucosylated glycosphingolipids that are synthesized by exocrine epithelial cells and circulate in body fluids. The glycosphingolipids function in embryogenesis, tissue differentiation, tumor metastasis, inflammation, and bacterial adhesion. They are secondarily absorbed to red blood cells giving rise to their Lewis phenotype. This gene is a member of the fucosyltransferase family, which catalyzes the addition of fucose to precursor polysaccharides in the last step of Lewis antigen biosynthesis. It encodes an enzyme with alpha(1,3)-fucosyltransferase and alpha(1,4)-fucosyltransferase activities. Mutations in this gene are responsible for the majority of Lewis antigen-negative phenotypes. Multiple alternatively spliced variants, encoding the same protein, have been found for this gene. [provided by RefSeq, Jul 2008]

Research_area:Others

Target_protein:CD174

applications:FCM

Reactivity:Human

Clonality:Monoclonal

Clone ID:1F8G5C7

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:CD174

Immunogen:Purified recombinant fragment of human CD174 (AA: 199-361) expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Purified antibody in PBS with 0.05% sodium azide

Concentration:

Molecular weight(Da):42.1kDa

UniProt accession:P21217

Synonyms:FUT3, LE, Les, FT3B, FucT-III

GeneID:2525