CD11a Monoclonal Antibody

SKU: BT-MCA4341

Size:100μL

Background:ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling. Two transcript variants encoding different isoforms have been found for this gene.

Research_area:Others

Target_protein:CD11a

applications:WB, IHC, FCM

Reactivity:Human

Clonality:Monoclonal

Clone ID:5G7C5

Host:Mouse

Isotype:Mouse IgG2a

Gene Symbol/ Name:CD11a

Immunogen:Purified recombinant fragment of human CD11a (AA: extra 26-194) expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Purified antibody in PBS with 0.05% sodium azide

Concentration:

Molecular weight(Da):128.8kDa

UniProt accession:P20701

Synonyms:ITGAL, LFA-1, LFA1A

GeneID:3683