CCNB3 Monoclonal Antibody

SKU: BT-MCA2416

Size:100μL

Background:The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as positive regulators of cyclin-dependent kinases (CDKs), and thereby play an essential role in the control of the cell cycle. Different cyclins exhibit distinct expression and degradation patterns, which contribute to the temporal coordination of each mitotic event. Studies of similar genes in chicken and drosophila suggest that this cyclin may associate with CDC2 and CDK2 kinases, and may be required for proper spindle reorganization and restoration of the interphase nucleus. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Research_area:Cell biology, Epigenetics and nuclear signaling

Target_protein:CCNB3

applications:FCM

Reactivity:Human

Clonality:Monoclonal

Clone ID:4B4D8

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:CCNB3

Immunogen:Purified recombinant fragment of human CCNB3 (AA: 142-363) expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Purified antibody in PBS with 0.05% sodium azide

Concentration:

Molecular weight(Da):158kDa

UniProt accession:Q8WWL7

Synonyms:CYCB3

GeneID:85417