GeneBio Systems
CCDC88A Polyclonal Antibody
CCDC88A Polyclonal Antibody
SKU:E-AB-13059
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Size::120μL
Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.
Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.
Exp date:12 months
Category ID_II:Primary Antibodies
Category ID_III:Polyclonal Antibodies
Abbreviation:CCDC88A
Target Synonym:AKT iphosphorylation enhancer;Akt phosphorylation enhancer;APE;Ccdc88a;Coiled coil domain containing 88A;Coiled coil domain containing protein 88A;Coiled-coil domain-containing protein 88A;FLJ10392;G alpha interacting vesicle associated protein;G alpha-interacting vesicle-associated protein;Galpha interacting vesicle associated protein;Girders of actin filament;Girdin;GIV;GRDN;GRDN;HkRP1;Hook related protein 1;Hook-related protein 1;KIAA1212
Research Areas:Cancer;Neuroscience;Signal Transduction
Conjugation:Unconjugated
Host:Rabbit
Species reactivity:Human;Mouse
Application:IHC
Isotype:IgG
Clonality:Polyclonal
Clone NO.:
UNIProt ID:Q3V6T2
Accession:
Background:This gene encodes a member of the Girdin family of coiled-coil domain containing proteins. The encoded protein is an actin-binding protein that is activated by the serine/threonine kinase Akt and plays a role in cytoskeleton remodeling and cell migration. The encoded protein also enhances Akt signaling by mediating phosphoinositide 3-kinase (PI3K)-dependent activation of Akt by growth factor receptor tyrosine kinases and G protein-coupled receptors. Increased expression of this gene and phosphorylation of the encoded protein may play a role in cancer metastasis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Concentration:1 mg/mL
Immunogen:Synthetic peptide of human CCDC88A
Buffer:PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification method:Affinity purification
Dilution:IHC 1:50-1:200
Calculated MW:
ObservedMW:
