Cav2.2 rabbit pAb

SKU: ES20796

Size: 100μL

Source:Rabbit

Applications:IHC;IF

Reactivity:Human;Rat;Mouse

Dilution:IHC 1:50-100

Immunogen:Synthetic Peptide of Cav2.2 AA range: 230-310

Storage_stability:-20°C/1 year

Clonality:Polyclonal

Isotype:IgG

Concentration:1 mg/ml

Observed_band(KD):263kD

Human_gene_id:774

Human_swiss_prot_no:Q00975

Subcellular_location:Membrane ; Multi-pass membrane protein .

Other_name:Voltage-dependent N-type calcium channel subunit alpha-1B (Brain calcium channel III;BIII;Calcium channel, L type, alpha-1 polypeptide isoform 5;Voltage-gated calcium channel subunit alpha Cav2.2)

Background:calcium voltage-gated channel subunit alpha1 B(CACNA1B) Homo sapiens The protein encoded by this gene is the pore-forming subunit of an N-type voltage-dependent calcium channel, which controls neurotransmitter release from neurons. The encoded protein forms a complex with alpha-2, beta, and delta subunits to form the high-voltage activated channel. This channel is sensitive to omega-conotoxin-GVIA and omega-agatoxin-IIIA but insensitive to dihydropyridines. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011],