CASTOR2 Antibody, Biotin conjugated - Cat. #: CSB-PA28239D0Rb

SKU: CSB-PA28239D0Rb

Size :50ul

Clone Number:

Aliases:CASTOR2 antibody; Cellular arginine sensor for mTORC1 protein 2 antibody; GATL2_HUMAN antibody; GATS-like protein 2 antibody; GATSL2 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:A6NHX0

Immunogen:Recombinant Human Cytosolic arginine sensor for mTORC1 subunit 2 protein (82-329AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA

Background:Functions as a negative regulator of the TORC1 signaling pathway through the GATOR complex. As part of homodimers or heterodimers with CASTOR1, directly binds and inhibits the GATOR subcomplex GATOR2 and thereby mTORC1. Does not directly bind arginine, but binding of arginine to CASTOR1 disrupts the interaction of CASTOR2-containing heterodimers with GATOR2 which can in turn activate mTORC1 and the TORC1 signaling pathway.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:Biotin

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:CASTOR2

Research Areas:Others