Caspase-3 (4B8) Mouse mAb

SKU: EM1266

Size: 100μL

Source:Mouse

Applications:IHC

Reactivity:Human, Rat, Mouse

Dilution:IHC 1:100-200

Immunogen:Synthetic Peptide

Storage_stability:PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Clonality:Monoclonal

Isotype:IgG1

Concentration:1mg/mL

Observed_band(KD):17,32kDa

Human_gene_id:836

Human_swiss_prot_no:P42574

Subcellular_location:Cytoplasm

Other_name:APOPAIN antibody, CASP 3 antibody, CPP32 antibody, Cysterine protease CPP32 antibody

Background:Caspase-3 (CPP-32, Apoptain, Yama, SCA-1) is a critical executioner of apoptosis, as it is either partially or totally responsible for the proteolytic cleavage of many key proteins such as the nuclear enzyme poly(ADP-ribose) polymerase (PARP).