Carboxypeptidase B2 Polyclonal Antibody

SKU: E-AB-40640

Size: 100μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: CPB2

Target Synonym: Carboxypeptidase B2;Carboxypeptidase U;CPU;Plasma carboxypeptidase B;pCPB;Thrombin-activable fibrinolysis inhibitor;TAFI;CPB2

Research Areas: Cardiovascular;Signal Transduction;Metabolism

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human

Application: WB

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: Q96IY4

Accession:

Background: CPB2 (Carboxypeptidase B2; also CPU and TAFI) is a secreted,50-60 kDa glycoprotein member of the peptidase M14 family of enzymes. It is expressed by hepatocytes (60 kDa) and platelets (50 kDa),with MW differences attributable to glycosylation. CPB2 is cleaved by thrombin and plasmin,generating a 36 kDa,relatively insoluble nonglycosylated enzymatically active fragment (TAFIa).

Concentration: 1 mg/mL

Immunogen: Recombinant Human CPB2 protein expressed by E.coli.

Buffer: PBS with 0.02% sodium azide,1% protective protein and 50% glycerol,pH7.4

Purification method: Antigen Affinity Purification

Dilution: WB 1:250-1:500

Calculated MW: 48 kDa

ObservedMW: 56 kDa