Cadherin-23 rabbit pAb

SKU: ES7147

Size: 100μL

Source:Rabbit

Applications:IF;ELISA

Reactivity:Human;Mouse;Rat

Dilution:Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.

Immunogen:The antiserum was produced against synthesized peptide derived from human CDH23. AA range:61-110

Storage_stability:-20°C/1 year

Clonality:Polyclonal

Isotype:IgG

Concentration:1 mg/ml

Observed_band(KD):

Human_gene_id:64072

Human_swiss_prot_no:Q9H251

Subcellular_location:Cell membrane ; Single-pass type I membrane protein .

Other_name:CDH23; KIAA1774; KIAA1812; Cadherin-23; Otocadherin

Background:This gene is a member of the cadherin superfamily, whose genes encode calcium dependent cell-cell adhesion glycoproteins. The encoded protein is thought to be involved in stereocilia organization and hair bundle formation. The gene is located in a region containing the human deafness loci DFNB12 and USH1D. Usher syndrome 1D and nonsyndromic autosomal recessive deafness DFNB12 are caused by allelic mutations of this cadherin-like gene. Upregulation of this gene may also be associated with breast cancer. Alternative splice variants encoding different isoforms have been described. [provided by RefSeq, May 2013],