C8 β rabbit pAb

SKU: ES8518

Size: 100μL

Source:Rabbit

Applications:WB;ELISA

Reactivity:Human;Rat

Dilution:WB 1:500-2000, ELISA 1:10000-20000

Immunogen:The antiserum was produced against synthesized peptide derived from the Internal region of human C8B. AA range:371-420

Storage_stability:-20°C/1 year

Clonality:Polyclonal

Isotype:IgG

Concentration:1 mg/ml

Observed_band(KD):70kD

Human_gene_id:732

Human_swiss_prot_no:P07358

Subcellular_location:Secreted.

Other_name:Complement component C8 beta chain (Complement component 8 subunit beta)

Background:This gene encodes one of the three subunits of the complement component 8 (C8) protein. C8 is composed of equimolar amounts of alpha, beta and gamma subunits, which are encoded by three separate genes. C8 is one component of the membrane attack complex, which mediates cell lysis, and it initiates membrane penetration of the complex. This protein mediates the interaction of C8 with the C5b-7 membrane attack complex precursor. In humans deficiency of this protein is associated with increased risk of meningococcal infections. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013],