C2CD3 Antibody, FITC conjugated - Cat. #: CSB-PA673367LC01HU

SKU: CSB-PA673367LC01HU

Size :50ug

Clone Number:

Aliases:C2CD3 antibody; C2 domain-containing protein 3 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q4AC94

Immunogen:Recombinant Human C2 domain-containing protein 3 protein (2079-2265AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:

Background:Component of the centrioles that acts as a positive regulator of centriole elongation (PubMed:24997988). Promotes assembly of centriolar distal appendage, a structure at the distal end of the mother centriole that acts as an anchor of the cilium, and is required for recruitment of centriolar distal appendages proteins CEP83, SCLT1, CEP89, FBF1 and CEP164. Not required for centriolar satellite integrity or RAB8 activation. Required for primary cilium formation (PubMed:23769972). Required for sonic hedgehog/SHH signaling and for proteolytic processing of GLI3.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:FITC

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:C2CD3

Research Areas:Others