c-Jun (Phospho Ser249) rabbit pAb

SKU: ES20155

Size: 100μL

Source:Rabbit

Applications:WB; ELISA

Reactivity:Human;Mouse;Rat

Dilution:WB 1:1000-2000 ELISA 1:5000-20000

Immunogen:Synthesized peptide derived from human c-Jun (Phospho Ser249)

Storage_stability:-20°C/1 year

Clonality:Polyclonal

Isotype:IgG

Concentration:1 mg/ml

Observed_band(KD):39-42kD

Human_gene_id:3725

Human_swiss_prot_no:P05412

Subcellular_location:Nucleus.

Other_name:Transcription factor AP-1 (Activator protein 1;AP1;Proto-oncogene c-Jun;V-jun avian sarcoma virus 17 oncogene homolog;p39)

Background:function:Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'.,PTM:Phosphorylation enhances the transcriptional activity. Phosphorylated by PRKDC.,similarity:Belongs to the bZIP family.,similarity:Belongs to the bZIP family. Jun subfamily.,similarity:Contains 1 bZIP domain.,subunit:Heterodimer with either FOS or BATF3. Interacts with HIVEP3 (By similarity). Interacts with SMAD3/SMAD4 heterodimers. Interacts with MYBBP1A, SPIB and TCF20. Interacts with COPS5; indirectly leading to its phosphorylation. Interacts with DSIPI; this interaction inhibits the binding of active AP1 to its target DNA.,