c-Fms Polyclonal Antibody

SKU: E-AB-15772

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: CSF1R

Target Synonym: C FMS;CD 115;CD115;CD115 antigen;CFMS;Colony stimulating factor 1 receptor;Colony stimulating factor I receptor;CSF 1 R;CSF 1R;CSF-1 receptor;CSF-1-R;CSF1 R;CSF1R;CSF1R;CSFR;EC 2.7.10.1;FIM 2;FIM2;FMS;FMS proto oncogene;FMS protooncogene;HDLS;M-CSF Receptor;M-CSF-R;Macrophage colony stimulating factor 1 receptor;Macrophage colony stimulating factor I receptor;Macrophage colony-stimulating factor 1 receptor;McDonough feline sarcoma viral (v fms) oncogene homolog;MCSFR;Oncogen FMS;Proto-oncogene c-Fms;V-FMS McDonough feline sarcoma viral oncogen homolog;formerly

Research Areas: Cancer;Cardiovascular;Immunology;Signal Transduction

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human;Mouse;Rat

Application: WB

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: P07333

Accession:

Background: The protein encoded by this gene is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in this gene have been associated with a predisposition to myeloid malignancy. The first intron of this gene contains a transcriptionally inactive ribosomal protein L7 processed pseudogene oriented in the opposite direction.

Concentration: 0.5 mg/mL

Immunogen: Synthetic peptide of human CSF1R

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Dilution: WB 1:500-1:2000

Calculated MW: 108kDa

ObservedMW: