Bovine Inducible T-cell Costimulator, ICOS ELISA Kit

SKU: E2041Bo

Size:96 Tests-1 Kit

Background:Enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells. Essential both for efficient interaction between T and B-cells and for normal antibody responses to T-cell dependent antigens. Does not up-regulate the production of interleukin-2, but superinduces the synthesis of interleukin-10. Prevents the apoptosis of pre-activated T-cells. Plays a critical role in CD40-mediated class switching of immunoglobin isotypes (By similarity).

Research_area:Immunology

Applications:ELISA

Target_protein:ICOS

Reactivity:Bovine

Assay type:Sandwich

Sensitivity:5.63ng/L

Detection range:10-2000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Inducible T-cell Costimulator

Species:Bovine

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q58DF9

MASS(Da):23,953

GeneID:507026

Synonyms:CD antigen CD278;ICOS;Inducible T-cell costimulator

Gene names:ICOS

Standard solution:2400ng/L