Bovine Collectin-11,COLEC11 ELISA KIT

SKU: E0445Bo

Size:96 Tests-1 Kit

Background:Lectin that plays a role in innate immunity, apoptosis and embryogenesis. Calcium-dependent lectin that binds self and non-self glycoproteins presenting high mannose oligosaccharides with at least one terminal alpha-1,2-linked mannose epitope. Primarily recognizes the terminal disaccharide of the glycan. Also recognizes a subset of fucosylated glycans and lipopolysaccharides. Plays a role in innate immunity through its ability to bind non-self sugars presented by microorganisms and to activate the complement through the recruitment of MAPS1. Also plays a role in apoptosis through its ability to bind in a calcium-independent manner the DNA present at the surface of apoptotic cells and to activate the complement in response to this binding. Finally, plays a role in development, probably serving as a guidance cue during the migration of neural crest cells and other cell types during embryogenesis. {ECO:0000250|UniProtKB:Q9BWP8}.

Research_area:

Applications:ELISA

Target_protein:COLEC11

Reactivity:Bovine

Assay type:Sandwich

Sensitivity:1.88ng/L

Detection range:3.75-240ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:

Species:Bovine

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q17QH6

MASS(Da):28333

GeneID:613991

Synonyms:COLEC11

Gene names:COLEC11

Standard solution:480ng/L