BLOC1S2 Antibody - Cat. #: CSB-PA754307ESR1HU

SKU: CSB-PA754307ESR1HU

Size :50ul

Clone Number:

Aliases:Biogenesis of lysosome-related organelles complex 1 subunit 2 antibody; BL1S2_HUMAN antibody; BLOC-1 subunit 2 antibody; Bloc1s2 antibody; BLOS2 antibody; Centrosome-associated protein antibody; RP11 316M21.4 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q6QNY1

Immunogen:Recombinant Human Biogenesis of lysosome-related organelles complex 1 subunit 2 protein (44-142AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background:Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking. May play a role in cell proliferation.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen Affinity Purified

Conjugate:Non-conjugated

Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:BLOC1S2

Research Areas:Epigenetics and Nuclear Signaling; Signal transduction