BLNK Polyclonal Antibody

SKU: E-AB-52474

Size::120μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Polyclonal Antibodies

Abbreviation:BLNK

Target Synonym:AGM4;B cell adapter containing SH2 domain protein;B cell adapter containing Src homology 2 domain protein;B cell adaptor containing SH2 domain;B cell linker;B cell linker protein;B cell-specific adaptor protein;B-cell activation;B-cell adapter containing a SH2 domain protein;B-cell adapter containing a Src homology 2 domain protein;B-cell linker protein;BASH;Bca;BLNK;BLNK s;BLNK;Cytoplasmic adapter protein;Ly 57;Ly57;Lymphocyte antigen 57;Lyw 57;Lyw57;MGC111051;SH2 domain-containing leukocyte protein;65-KD;SLP 65;SLP-65;SLP65;Src homology [SH2] domain-containing leukocyte protein of 65 kD;Src homology 2 domain containing leukocyte protein of 65 kDa;Src homology 2 domain-containing leukocyte protein of 65 kDa

Research Areas:Immunology;Signal Transduction

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:IHC

Isotype:IgG

Clonality:Polyclonal

Clone NO.:

UNIProt ID:Q8WV28

Accession:

Background:This gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia and absent B cells, a disease in which the pro- to pre-B-cell transition is developmentally blocked. Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia.

Concentration:1.1 mg/mL

Immunogen:Fusion protein of human BLNK

Buffer:PBS with 0.05% NaN3 and 40% Glycerol,pH7.4

Purification method:Antigen affinity purification

Dilution:IHC 1:50-1:300

Calculated MW:

ObservedMW: