Biotin Anti-Mouse CD132 Antibody[3E12]

SKU: GBS-F1015B

Size:100μg

Storage:This product can be stored at 2-8°C for 12 months. Do not freeze.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Flow Cytometry Antibodies

Abbreviation:CD132

Target Synonym:CD132;Cytokine receptor common subunit gamma;IL-2 receptor subunit gamma;IL-2R subunit gamma;IL-2RG;Il2rg;Interleukin-2 receptor subunit gamma;gammaC;p64

Research Areas:Immunology

Conjugation:Biotin

Host:Rat

Species reactivity:Mouse

Application:FCM

Usage:Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 10⁶ cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

Isotype:Rat IgG2b, κ

Clonality:Monoclonal

Clone NO.:3E12

UNIProt ID:P34902

Background:CD132 is a 64-70 kD type I transmembrane glycoprotein of the Ig superfamily, and is also known as common γ chain (γc) or IL-2 receptor γ subunit. It is expressed broadly on T- and B-lymphocytes, NK cells, monocytes, and granulocytes. CD132 is an essential component of cytokine receptors for IL-2, IL-4, IL-7, IL-9, IL-15, and IL-21. Ligand binding induces tyrosine phosphorylation and initiates signaling through a JAK/STAT pathway. CD132 mutation results in X-linked severe combined immune deficiency (XSCID).

Concentration:0.5 mg/mL

Control catalog number:E-AB-F09843B

Immunogen:

Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

Purification method:

Dilution:

GeneID:16186