Biotin Anti-Human CD62L Antibody[DREG56]

SKU: GBS-F1051B

Size:100μg

Storage:This product can be stored at 2-8°C for 12 months. Do not freeze.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Flow Cytometry Antibodies

Abbreviation:CD62L

Target Synonym:CD62L;CD62 antigen-like family member L;L-selectin;LAM-1;LECAM1;Lnhr;Ly-22;Ly22;Lymph node homing receptor;Sell

Research Areas:Cell Adhesion;Cell Biology;Costimulatory Molecules;Immunology;Innate Immunity

Conjugation:Biotin

Host:Mouse

Species reactivity:Human

Application:FCM

Usage:Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 10⁶ cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

Isotype:Mouse IgG1, κ

Clonality:Monoclonal

Clone NO.:DREG56

UNIProt ID:P14151

Background:CD62L is a 74-95 kD single chain type I glycoprotein referred to as L-selectin or LECAM-1. It is expressed on most peripheral blood B cells, subsets of T and NK cells, monocytes, granulocytes, and certain hematopoietic malignant cells. CD62L binds to carbohydrates present on certain glycoforms of CD34, glycam-1, and MAdCAM-1 and with a low affinity to anionic oligosaccharide sequences related to sialylated Lewis X (sLex, CD15s) through its C-type lectin domain. CD62L is important for the homing of naïve lymphocytes to high endothelial venules in peripheral lymph nodes and Peyer's patches. It also plays a role in leukocyte rolling on activated endothelial cells.

Concentration:0.5 mg/mL

Control catalog number:E-AB-F09793B

Immunogen:

Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

Purification method:

Dilution:

GeneID:6402