Beclin-1(Phospho-Ser15) Rabbit Polyclonal Antibody

SKU: BT-AP06337

Size:100μL

Background:This gene encodes a protein that regulates autophagy| a catabolic process of degradation induced by starvation. The encoded protein is a component of the phosphatidylinositol-3-kinase (PI3K) complex which mediates vesicle-trafficking processes. This protein is thought to play a role in multiple cellular processes| including tumorigenesis| neurodegeneration and apoptosis. Alternative splicing results in multiple transcript variants.

Research_area:Cancer; Epigenetics and nuclear signaling; Metabolism; Microbiology

Target_protein:BECN1

applications:WB

Reactivity:Human, Mouse

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:Beclin-1

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):

UniProt accession:Human: Q14457; Mouse: O88597; Rat: Q91XJ1

Synonyms:Beclin-1 ;Ser15 ; Beclin-1; Coiled-coil myosin-like BCL2-interacting protein; Protein GT197

GeneID:Human: 8678; Mouse: 56208; Rat: 114558