BCL2 antibody , Cat. # FNab00840

SKU: FNab00840

Size:100ug

Purification:Protein A+G purification

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Mouse

Clonality:monoclonal

Clone ID:8A10

Isotype:IgG2a

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor(APAF-1). May attenuate inflammation by impairing NLRP1-inflammasome activation, hence CASP1 activation and IL1B release(PubMed:17418785).

Immunogen:B-cell CLL/lymphoma 2

Synonyms:Apoptosis regulator Bcl 2, B cell CLL/lymphoma 2, BCL2, Oncogene B cell leukemia 2

Observed MW:26 kDa

Uniprot ID:P10415

Reactivity:Human

Tested Application:ELISA, WB, IP, IHC

Recommended dilution:WB: 1:1000-1:10000; IP: 1:500-1:5000; IHC: 1:100-1:2000

Gene ID:596

Research Area:Neuroscience, Cancer, Immunology, Cardiovascular