BACE (Acetyl Lys316) Rabbit Polyclonal Antibody

SKU: BT-AP00713

Size:100μL

Background:This gene encodes a member of the peptidase A1 family of aspartic proteases. Alternative splicing results in multiple transcript variants| at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protease. This transmembrane protease catalyzes the first step in the formation of amyloid beta peptide from amyloid precursor protein. Amyloid beta peptides are the main constituent of amyloid beta plaques| which accumulate in the brains of human Alzheimer's disease patients.

Research_area:Cell biology; Neuroscience

Target_protein:BACE1

applications:WB, ELISA

Reactivity:Human, Mouse, Rat

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:BACE

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):55110

UniProt accession:Human: P56817; Mouse: P56818; Rat: P56819

Synonyms:BACE ;Acetyl Lys316; Beta-secretase 1; EC 3.4.23.46; Aspartyl protease 2; ASP2; Asp 2; Beta-site amyloid precursor protein cleaving enzyme 1; Beta-site APP cleaving enzyme 1; Memapsin-2; Membrane-associated aspartic protease 2

GeneID:Human: 23621; Mouse: 23821; Rat: 29392