B3GALT4 Monoclonal Antibody

SKU: BT-MCA3791

Size:100μL

Background:This gene is a member of the beta-1,3-galactosyltransferase (beta3GalT) gene family. This family encodes type II membrane-bound glycoproteins with diverse enzymatic functions using different donor substrates (UDP-galactose and UDP-N-acetylglucosamine) and different acceptor sugars (N-acetylglucosamine, galactose, N-acetylgalactosamine). The beta3GalT genes are distantly related to the Drosophila Brainiac gene and have the protein coding sequence contained in a single exon. The beta3GalT proteins also contain conserved sequences not found in the beta4GalT or alpha3GalT proteins. The carbohydrate chains synthesized by these enzymes are designated as type 1, whereas beta4GalT enzymes synthesize type 2 carbohydrate chains. The ratio of type 1:type 2 chains changes during embryogenesis. By sequence similarity, the beta3GalT genes fall into at least two groups: beta3GalT4 and 4 other beta3GalT genes (beta3GalT1-3, beta3GalT5). This gene is oriented telomere to centromere in close proximity to the ribosomal protein S18 gene. The functionality of the encoded protein is limited to ganglioseries glycolipid biosynthesis.

Research_area:Others

Target_protein:B3GALT4

applications:WB, FCM

Reactivity:Human

Clonality:Monoclonal

Clone ID:5F12B8

Host:Mouse

Isotype:Mouse IgG2a

Gene Symbol/ Name:B3GALT4

Immunogen:Purified recombinant fragment of human B3GALT4 (AA: 191-359) expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Purified antibody in PBS with 0.05% sodium azide.

Concentration:

Molecular weight(Da):41.5kDa

UniProt accession:O96024

Synonyms:GALT2, GALT4, BETA3GALT4

GeneID:8705