ATP5C1 antibody , Cat. # FNab00705

SKU: FNab00705

Size:100ug

Purification:Protein A+G purification

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Mouse

Clonality:monoclonal

Clone ID:8H11

Isotype:IgG1

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:Mitochondrial membrane ATP synthase(F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1)-containing the extramembraneous catalytic core, and F(0)-containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(1) domain and the central stalk which is part of the complex rotary element. The gamma subunit protrudes into the catalytic domain formed of alpha(3)beta(3). Rotation of the central stalk against the surrounding alpha(3)beta(3) subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits.

Immunogen:ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1

Synonyms:ATP5C, ATP5C1, ATP5CL1, F ATPase gamma subunit

Observed MW:33 kDa

Uniprot ID:P36542

Reactivity:Human

Tested Application:ELISA, WB, IHC

Recommended dilution:WB: 1:500-1:2000; IHC: 1:100-1:500

Gene ID:509

Research Area:Metabolism