ASIC1 rabbit pAb

SKU: ES8643

Size: 100μL

Source:Rabbit

Applications:WB;IHC;IF;IHC-f;ELISA

Reactivity:Human;Mouse;Rat

Dilution:WB 1:500-2000,IHC-p 1:500-200, ELISA 1:10000-20000

Immunogen:Synthetic peptide from human protein at AA range: 220-280

Storage_stability:-20°C/1 year

Clonality:Polyclonal

Isotype:IgG

Concentration:1 mg/ml

Observed_band(KD):55kD

Human_gene_id:41

Human_swiss_prot_no:P78348

Subcellular_location:Cell membrane ; Multi-pass membrane protein . Localizes in synaptosomes at dendritic synapses of neurons. Colocalizes with DLG4 (By similarity). .

Other_name:Acid-sensing ion channel 1 (ASIC1;Amiloride-sensitive cation channel 2, neuronal;Brain sodium channel 2;BNaC2)

Background:This gene encodes a member of the acid-sensing ion channel (ASIC) family of proteins, which are part of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. Members of the ASIC family are sensitive to amiloride and function in neurotransmission. The encoded proteins function in learning, pain transduction, touch sensation, and development of memory and fear. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2012],