ASH2L Antibody - Cat. #: CSB-PA972879

SKU: CSB-PA972879

Size :100ul

Clone Number:

Aliases:ASH 2 antibody; Ash2 (absent small or homeotic) like antibody; Ash2 (absent; small; or homeotic) like (Drosophila) antibody; ASH2 antibody; ASH2 LIKE antibody; ASH2 like protein antibody; ASH2-like protein antibody; Ash2l antibody; ASH2L_HUMAN antibody; ASH2L1 antibody; ASH2L2 antibody; Bre 2 antibody; Bre2 antibody; Discs 2-like antibody; Drosophila absent; small; or homeotic antibody; Drosophila ASH2-like antibody; Set1/Ash2 histone methyltransferase complex subunit ASH2 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q9UBL3

Immunogen:Peptide sequence around aa.620~624(G-R-R-S-P) derived from Human ASH2L.

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, WB; WB:1:500-1:1000

Background:Component of the Set1/Ash2 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3, but not if the neighboring 'Lys-9' residue is already methylated. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. May function as a transcriptional regulator. May play a role in hematopoiesis.

Wysocka J., Myers M.P., Laherty C.D., Eisenman R.N., Herr W.Genes Dev. 17:896-911(2003)
Patel A., Dharmarajan V., Vought V.E., Cosgrove M.S.J. Biol. Chem. 284:24242-24256(2009)

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Conjugate:Non-conjugated

Buffer:Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:ASH2L

Research Areas:Epigenetics and Nuclear Signaling;Cancer