ARNT Antibody - Cat. #: CSB-PA174700

SKU: CSB-PA174700

Size :100ul

Clone Number:

Aliases:arnT antibody; ARNT protein antibody; ARNT_HUMAN antibody; Aryl hydrocarbon receptor nuclear translocator antibody; bHLHe2 antibody; Class E basic helix-loop-helix protein 2 antibody; Dioxin receptor antibody; Dioxin receptor nuclear translocator antibody; Drnt antibody; HIF 1 beta antibody; HIF 1beta antibody; HIF-1-beta antibody; HIF1-beta antibody; HIF1B antibody; HIF1beta antibody; Hypoxia Inducible Factor 1 antibody; Hypoxia inducible factor 1 beta antibody; Hypoxia-inducible factor 1-beta antibody; nuclear translocator antibody; Tango antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P27540

Immunogen:Synthesized peptide derived from internal of Human ARNT.

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, WB; WB:1:500-1:3000

Background:Required for activity of the Ah (dioxin) receptor. This protein is required for the ligand-binding subunit to translocate from the cytosol to the nucleus after ligand binding. The complex then initiates transcription of genes involved in the activation of PAH procarcinogens. The heterodimer with HIF1A or EPAS1/HIF2A functions as a transcriptional regulator of the adaptive response to hypoxia.

Hoffman E.C., Science 252:954-958(1991).
Wang G.L., Proc. Natl. Acad. Sci. U.S.A. 92:5510-5514(1995).
Nguyen T.A., Arch. Biochem. Biophys. 367:250-257(1999).

Clonality:Polyclonal

Isotype:IgG

Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:ARNT

Research Areas:Epigenetics and Nuclear Signaling;Cancer?Cardiovascular;Metabolism