ARHGEF7 antibody , Cat. # FNab00564

SKU: FNab00564

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:Acts as a RAC1 guanine nucleotide exchange factor(GEF) and can induce membrane ruffling. Functions in cell migration, attachment and cell spreading. Promotes targeting of RAC1 to focal adhesions(By similarity). May function as a positive regulator of apoptosis. Downstream of NMDA receptors and CaMKK-CaMK1 signaling cascade, promotes the formation of spines and synapses in hippocampal neurons.

Immunogen:Rho guanine nucleotide exchange factor(GEF) 7

Synonyms:COOL1, KIAA0142, P85SPR, PAK3BP, PIXB

Observed MW:70 kDa

Uniprot ID:Q14155

Reactivity:Human, Mouse, Rat

Tested Application:ELISA, IP, WB

Recommended dilution:WB: 1:1000-1:4000; IP: 1:500-1:2000

Gene ID:8874

Research Area:Signal Transduction