APOA1 Monoclonal Antibody

SKU: BT-MCA4399

Size:100μL

Background:APOA1: apolipoprotein A-I, it is the major protein component of high density lipoprotein (HDL) in plasma. The protein promotes cholesterol efflux from tissues to the liver for excretion, and it is a cofactor for lecithin cholesterolacyltransferase (LCAT) which is responsible for the formation of most plasma cholesteryl esters. Defects in the Apolipoprotein A I gene are associated with HDL deficiency and Tangier disease. The therapeutic potential of apoA-I has been recently assessed in patients with acute coronary syndromes, using a recombinant form of a naturally occurring variant of apoA-I. The availability of recombinant normal apoA-I should facilitate further investigation into the potential usefulness of apoA-I in preventing atherosclerotic vascular diseases.

Research_area:Cardiovascular, Neuroscience

Target_protein:APOA1

applications:WB

Reactivity:Human

Clonality:Monoclonal

Clone ID:5F4F5

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:APOA1

Immunogen:Purified recombinant fragment of human APOA1 expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Ascitic fluid containing 0.03% sodium azide.

Concentration:

Molecular weight(Da):25kDa

UniProt accession:P02647

Synonyms:MGC117399

GeneID: