APLF antibody , Cat. # FNab00484

SKU: FNab00484

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:Nuclease involved in single-strand and double-strand DNA break repair. Recruited to sites of DNA damage through interaction with poly(ADP-ribose), a polymeric post-translational modification synthesized transiently at sites of chromosomal damage to accelerate DNA strand break repair reactions. Displays apurinic-apyrimidinic(AP) endonuclease and 3'-5' exonuclease activities in vitro. Also able to introduce nicks at hydroxyuracil and other types of pyrimidine base damage.

Immunogen:aprataxin and PNKP like factor

Synonyms:C2orf13, PALF, XIP1

Observed MW:60 kD

Uniprot ID:Q8IW19

Reactivity:Human

Tested Application:ELISA, WB

Recommended dilution:WB: 1:500 - 1:2000

Gene ID:200558

Research Area:Metabolism