APEX1 Polyclonal Antibody

SKU: E-AB-13896

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: APEX1

Target Synonym: AP endonuclease 1;AP endonuclease class I;AP lyase;APE 1;APE;APE-1;APEN;APEX 1;APEX;APEX nuclease (multifunctional DNA repair enzyme) 1;Apex nuclease 1;APEX nuclease;APEX1;APEX1;Apurinic endonuclease;Apurinic-apyrimidinic endonuclease 1;Apurinic/apyrimidinic (abasic) endonuclease;Apurinic/apyrimidinic endonuclease 1;Apurinic/apyrimidinic exonuclease;APX;BAP1;Deoxyribonuclease (apurinic or apyrimidinic);DNA (apurinic or apyrimidinic site) lyase;DNA-(apurinic or apyrimidinic site) lyase;mitochondrial;EC 4.2.99.18;HAP 1;HAP1;Human Apurinic endonuclease 1;MGC139790;Multifunctional DNA repair enzyme;Redox factor 1;Redox factor-1;REF 1;REF 1 protein;REF-1;REF1;REF1 protein

Research Areas: Cancer;Cardiovascular;Epigenetics and Nuclear Signaling

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human;Mouse;Rat

Application: WB

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: P27695

Accession:

Background: Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes the major AP endonuclease in human cells. Splice variants have been found for this gene; all encode the same protein.

Concentration: 0.2 mg/mL

Immunogen: Recombinant protein of human APEX1

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method: Affinity purification

Dilution: WB 1:500-1:2000

Calculated MW: 36kDa

ObservedMW: