APAF1 antibody , Cat. # FNab00470

SKU: FNab00470

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9(Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. Isoform 6 is less effective in inducing apoptosis.

Immunogen:apoptotic peptidase activating factor 1

Synonyms:APAF 1, APAF1, CED4, KIAA0413

Observed MW:140 kDa

Uniprot ID:O14727

Reactivity:Human, Mouse, Rat

Tested Application:ELISA, WB, IHC, IP, IF

Recommended dilution:WB: 1:500-1:2000; IP: 1:500-1:1000; IHC: 1:50-1:500; IF: 1:20-1:200

Gene ID:317

Research Area:Developmental biology