APAF1 Antibody - Cat. #: CSB-PA001885LA01HU

SKU: CSB-PA001885LA01HU

Size :50ug

Clone Number:

Aliases:APAF 1 antibody; Apaf-1 antibody; APAF_HUMAN antibody; Apaf1 antibody; Apoptotic peptidase activating factor 1 antibody; Apoptotic protease activating factor 1 antibody; Apoptotic protease activating factor antibody; Apoptotic protease-activating factor 1 antibody; CED 4 antibody; CED4 antibody; KIAA0413 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:O14727

Immunogen:Recombinant Human Apoptotic protease-activating factor 1 protein (104-415AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200

Background:Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. Isoform 6 is less effective in inducing apoptosis.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:Non-conjugated

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:APAF1

Research Areas:Cancer; Cell biology; Metabolism