Anti-TTC38 Antibody Picoband®

SKU: A16794-1

Size: 100 μg

Storage: At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human

Applications: WB,ICC,IF,Flow Cytometry,ELISA

Application Details: Western blot, 0.25-0.5 μg/ml, Human
Immunocytochemistry/Immunofluorescence, 5 μg/ml, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/ml, -

Gene Name: TTC38

Specificity:

Background: TTC38 (tetratricopeptide repeat domain 38) is a 469 amino acid protein that contains three TPR repeats and belongs to the TTC38 family. The gene that encodes TTC38 consists of over 26,000 bases and maps to 22q13. Housing over 500 genes, chromosome 22 is the second smallest chromosome in the human genome. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, Neurofibromatosis type 2, autism and schizophrenia. In addition, translocations between chromosomes 9 and 22 may lead to the formation of the Philadelphia Chromosome and the subsequent production of the novel fusion protein BCR-Abl, a potent cell proliferation activator found in several types of leukemias.

Immunogen: E.coli-derived human TTC38 recombinant protein (Position: E267-Q469).

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Vinayagam, A. , Stelzl, U. , Foulle, R. , Plassmann, S. , Zenkner, M. , & Timm, J. , et al. (2011). A ed protein interaction network for investigating Fixed signal transduction. Science Signaling, 4(189), rs8. 2. Xin, S. A. , Yh, E. , Ys, D. , Cw, B. , Gy, E. , & Hc, F. , et al. (2021). The involvement of parkin-dependent mitophagy in the anti-cancer activity of ginsenoside. Journal of Ginseng Research. 3. Lamesch, P. , Li, N. , Milstein, S. , Fan, C. , & Hao, T. . (2007). Horfeome v3.1: a resource of human open reading frames representing over 10,000 human genes. Genomics, 89( 3), 307-315.

Uniprot ID: Q5R3I4

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins.

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 53 kDa

Calculated Molecular Weight: 24145 MW

Gene ID: 55020

Protein Name: Tetratricopeptide repeat protein 38

Gene Full Name: tetratricopeptide repeat domain 38

Synonyms: TTC38; Tetratricopeptide repeat protein 38; TPR repeat protein 38