Anti-Tenascin-R TNR Antibody Picoband®

SKU: PA1695-1

Size: 100 μg

Storage: Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.

Form: Lyophilized

Reactivity: Human,Mouse,Rat

Applications: Flow Cytometry,IHC,WB

Application Details: Western blot, 0.1-0.5μg/ml, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Human, Mouse, Rat
Flow Cytometry(Fixed), 1-3 μg/1x10⁶ cells, Human

Gene Name: TNR

Specificity: No cross reactivity with other proteins.

Background: Tenascin-R is a protein that in humans is encoded by the TNR gene. Tenascin-R (TNR) is an extracellular matrix protein expressed primarily in the central nervous system. It is a member of the tenascin (TN) gene family, which includes at least 3 genes in mammals: TNC (or hexabrachion), TNX (TNXB), and TNR. The genes are expressed in distinct tissues at different times during embryonic development and are present in adult tissues. TNR has been detected predominantly in the central nervous system and is localized around motor neurons and on motor axons in the spinal cord, cerebellum, hippocampus, and olfactory bulb. It is suggested that tenascin-R has a role in initiating the detachment of neuroblasts from tangential chains and in initiating radial migration of the cells.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of mouse TNR, identical to the related rat sequence, and different from the related human sequence by one amino acid.

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Reference: 1. Leprini, A., Gherzi, R., Siri, A., Querze, G., Viti, F., Zardi, L.The human tenascin-R gene.J. Biol. Chem. 271: 31251-31254, 1996. 2. Saghatelyan, A., de Chevigny, A., Schachner, M., Lledo, P.-M.Tenascin-R mediates activity-dependent recruitment of neuroblasts in the adult mouse forebrain.Nature Neurosci. 7: 347-356, 2004. 3. Williams, H., Schachner, M., Wang, B., Kenwrick, S.Radiation hybrid mapping of the genes for tenascin-R (TNR), phosducin (PDC), Laminin C1 (LAMC1), and TAX in 1q25-q32.Genomics 46: 165-166, 1997.

Uniprot ID: Q8BYI9

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 180-250 kDa

Calculated Molecular Weight: 150 kDa

Gene ID: 7143

Protein Name: Tenascin-R

Gene Full Name: tenascin R

Synonyms: Janusin antibody; MGC149328 antibody; Restrictin antibody; Tenascin R(restrictin, janusin) antibody; Tenascin-R antibody; TENR_HUMAN antibody; TN-R antibody; Tnr antibody