Anti-SYCN Antibody Picoband®

SKU: A17780-1

Size: 100 μg

Storage: At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human,Mouse,Rat

Applications: WB,ICC,IF,Flow Cytometry,ELISA

Application Details: Western blot, 0.25-0.5 μg/ml, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/ml, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/ml, -

Gene Name: SYCN

Specificity:

Background: SYCN functions in exocytosis in pancreatic acinar cells regulating the fusion of zymogen granules with each other. SYCN may have a pore-forming activity on membranes and regulate exocytosis in other exocrine tissues.

Immunogen: E.coli-derived human SYCN recombinant protein (Position: A19-S134). Human SYCN shares 73.9% and 72.2% amino acid (aa) sequence identity with mouse and rat SYCN, respectively.

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Antonin, W., Wagner, M., Riedel, D., Brose, N., Jahn, R. Loss of the zymogen granule protein syncollin affects pancreatic protein synthesis and transport but not secretion. Molec. Cell. Biol. 22: 1545-1554, 2002. 2. Bach, J. P., Borta, H., Ackermann, W., Faust, F., Borchers, O., Schrader, M. The secretory granule protein syncollin localizes to HL-60 cells and neutrophils. J. Histochem. Cytochem. 54: 877-888, 2006. 3. Edwardson, J. M., An, S., Jahn, R. The secretory granule protein syncollin binds to syntaxin in a Ca2(+)-sensitive manner. Cell 90: 325-333, 1997.

Uniprot ID: Q0VAF6

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross reactivity with other proteins.

Isotype: IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 14 kDa

Calculated Molecular Weight: 52588 MW

Gene ID: 342898

Protein Name: Syncollin

Gene Full Name: syncollin

Synonyms: SYCN; INSSA1; SYL; Syncollin; Insulin synthesis-associated protein 1