Anti-ST13 Antibody Picoband®

SKU: A05692-1

Size: 100 μg

Storage: At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human,Mouse,Rat

Applications: WB,ICC,IF,Flow Cytometry,ELISA

Application Details: Western blot, 0.1-0.25 μg/ml, Human
Immunocytochemistry/Immunofluorescence, 5 μg/ml, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/ml, -

Gene Name: ST13

Specificity:

Background: Hsc70-interacting protein also known as suppression of tumorigenicity 13 (ST13) is a protein that in humans is encoded by the ST13 gene. The protein encoded by this gene is an adaptor protein that mediates the association of the heat shock proteins HSP70 and HSP90. This protein has been shown to be involved in the assembly process of glucocorticoid receptor, which requires the assistance of multiple molecular chaperones. The expression of this gene is reported to be downregulated in colorectal carcinoma tissue suggesting that it is a candidate tumor suppressor gene. Alternative splicing results in multiple transcript variants encoding different isoforms.

Immunogen: E.coli-derived human ST13 recombinant protein (Position: D2-A369).

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Cao, J., Cai, X., Zheng, L., Geng, L., Shi, Z., Pao, C. C., Zheng, S. Characterization of colorectal-cancer-related cDNA clones obtained by subtractive hybridization screening. J. Cancer Res. Clin. Oncol. 123: 447-451, 1997. 2. Hohfeld, J., Minami, Y., Hartl, F.-U. Hip, a novel cochaperone involved in the eukaryotic Hsc70/Hsp40 reaction cycle. Cell 83: 589-598, 1995. 3. Howarth, J. L., Glover, C. P. J., Uney, J. B. HSP70 interacting protein prevents the accumulation of inclusions in polyglutamine disease. J. Neurochem. 108: 945-951, 2009.

Uniprot ID: P50502

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 45-54 kDa

Calculated Molecular Weight: 101272 MW

Gene ID: 6767

Protein Name: Hsc70-interacting protein

Gene Full Name: ST13 Hsp70 interacting protein

Synonyms: AAG2; FAM10A1; FAM10A4; HIP; HOP; Hsc70 interacting protein; HSPABP; HSPABP1; P48; PRO0786; Protein FAM10A1; Putative tumor suppressor ST13; SNC6; ST13