Anti-SLC22A3 Antibody Picoband®

SKU: A04914-1

Size: 100 μg

Storage: Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.

Form: Lyophilized

Reactivity: Human,Mouse

Applications: WB,Flow Cytometry

Application Details: Western blot, 0.25-0.5μg/ml, Human, Mouse
Flow Cytometry (Fixed), 1-3μg/1x10⁶ cells, Human

Gene Name: SLC22A3

Specificity:

Background: Solute carrier family 22 (extraneuronal monoamine transporter), member 3, also known as SLC22A3 or OCT3 is a protein that in humans is encoded by the SLC22A3 gene. This gene is mapped to 6q25.3. Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. This gene mediates potential-dependent transport of a variety of organic cations. It may play a significant role in the disposition of cationic neurotoxins and neurotransmitters in the brain.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human SLC22A3, which shares 76.5% amino acid (aa) sequence identity with both mouse and rat SLC22A3.

Clonality: Polyclonal

Contents: Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.01mg NaN3.

Purification: Immunogen affinity purified.

Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Reference: 1. Lazar, A., Grundemann, D., Berkels, R., Taubert, D., Zimmermann, T., Schomig, E. Genetic variability of the extraneuronal monoamine transporter EMT (SLC22A3). J. Hum. Genet. 48: 226-230, 2003. 2. Nagano, T., Mitchell, J. A., Sanz, L. A., Pauler, F. M., Ferguson-Smith, A. C., Feil, R., Fraser, P. The Air noncoding RNA epigenetically silences transcription by targeting G9a to chromatin. Science 322: 1717-1720, 2008. 3. Sleutels, F., Zwart, R., Barlow, D. P. The non-coding Air RNA is required for silencing autosomal imprinted genes. Nature 415: 810-813, 2002.

Uniprot ID: O75751

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins.

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 61 kDa

Calculated Molecular Weight: 56903 MW

Gene ID: 6581

Protein Name: Solute carrier family 22 member 3

Gene Full Name: solute carrier family 22 member 3

Synonyms: solute carrier family 22 member 3; EMT; EMTH; OCT3; SLC22A3