Anti-Seryl-tRNA synthetase/SERS/SARS1 Antibody Picoband®

SKU: A00501-1

Size: 100 μg

Storage: At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human,Mouse,Rat

Applications: WB,ICC,IF,Flow Cytometry,ELISA

Application Details: Western blot, 0.1-0.25 μg/ml, Human, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5 μg/ml, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/ml, -

Gene Name: SARS1

Specificity:

Background: This gene belongs to the class II amino-acyl tRNA family. The encoded enzyme catalyzes the transfer of L-serine to tRNA (Ser) and is related to bacterial and yeast counterparts. Multiple alternatively spliced transcript variants have been described but the biological validity of all variants is unknown.

Immunogen: E.coli-derived human Seryl-tRNA synthetase/SERS/SARS1 recombinant protein (Position: K71-K483).

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Fukui, H., Hanaoka, R., Kawahara, A. Noncanonical activity of seryl-tRNA synthetase is involved in vascular development. Circ. Res. 104: 1253-1259, 2009. 2. Herzog, W., Muller, K., Huisken, J., Stainier, D. Y. R. Genetic evidence for a noncanonical function of seryl-tRNA synthetase in vascular development. Circ. Res. 104: 1260-1266, 2009. Note: Erratum: Circ. Res. 105: e54 only, 2009. 3. Lo, W.-S., Gardiner, E., Xu, Z., Lau, C.-F., Wang, F., Zhou, J. J., Mendlein, J. D., Nangle, L. A., Chiang, K. P., Yang, X.-L., Au, K.-F., Wong, W. H., Guo, M., Zhang, M., Schimmel, P. Human tRNA synthetase catalytic nulls with diverse functions. Science 345: 328-332, 2014.

Uniprot ID: P49591

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 59 kDa

Calculated Molecular Weight: 44565 MW

Gene ID: 6301

Protein Name: Serine--tRNA ligase, cytoplasmic

Gene Full Name: seryl-tRNA synthetase 1

Synonyms: SARS; Serine tRNA ligase; SERRS; SERS; seryl tRNA synthetase; Seryl tRNA(Ser/Sec) synthetase