Anti-SERINC5 Antibody Picoband®

SKU: A06603

Size: 100 μg

Storage: At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Form: Lyophilized

Reactivity: Human

Applications: WB,Flow Cytometry,ELISA

Application Details: Western blot, 0.25-0.5 μg/ml, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
ELISA, 0.1-0.5 μg/ml, -

Gene Name: SERINC5

Specificity:

Background: Serine incorporator 5 is a protein that in humans is encoded by the SERINC5 gene. Predicted to enable L-serine transmembrane transporter activity. Involved in defense response to virus; detection of virus; and innate immune response. Located in several cellular components, including centrosome; cytosol; and plasma membrane

Immunogen: E.coli-derived human SERINC5 recombinant protein (Position: E64-H394).

Clonality: Polyclonal

Contents: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Reference: 1. Gross, M. B. Personal Communication. Baltimore, Md. 3/23/2012. 2. Inuzuka, M., Hayakawa, M., Ingi, T. Serinc, an activity-regulated protein family, incorporates serine into membrane lipid synthesis. J. Biol. Chem. 280: 35776-35783, 2005. 3. Rosa, A., Chande, A., Ziglio, S., De Sanctis, V., Bertorelli, R., Goh, S. L., McCauley, S. M., Nowosielska, A., Antonarakis, S. E., Luban, J., Santoni, F. A., Pizzato, M. HIV-1 Nef promotes infection by excluding SERINC5 from virion incorporation. Nature 526: 212-217, 2015.

Uniprot ID: Q86VE9

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins.

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 65 kDa

Calculated Molecular Weight: 104553 MW

Gene ID: 256987

Protein Name: Serine incorporator 5

Gene Full Name: serine incorporator 5

Synonyms: C5orf12; SERINC5; serine incorporator 5; TPO1