Anti-SCG10/STMN2 Antibody Picoband®

SKU: A04729-2

Size: 100 μg

Storage: Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.

Form: Lyophilized

Reactivity: Human,Mouse,Rat

Applications: WB,IHC,ICC,IF,Flow Cytometry,ELISA

Application Details: Western blot, 0.25-0.5μg/ml, Human, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 2-5μg/ml, Mouse, Rat
Immunocytochemistry/Immunofluorescence, 5μg/ml, Human
Flow Cytometry (Fixed), 1-3μg/1x10⁶ cells, Human, Mouse
ELISA, 0.1-0.5μg/ml, -

Gene Name: STMN2

Specificity:

Background: Stathmin-2 is a protein that in humans is encoded by the STMN2 gene. This gene encodes a member of the stathmin family of phosphoproteins. Stathmin proteins function in microtubule dynamics and signal transduction. The encoded protein plays a regulatory role in neuronal growth and is also thought to be involved in osteogenesis. Reductions in the expression of this gene have been associated with Down's syndrome and Alzheimer's disease. Alternatively spliced transcript variants have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome 6.

Immunogen: E.coli-derived human SCG10/STMN2 recombinant protein (Position: S23-N170).

Clonality: Polyclonal

Contents: Each vial contains 4mg Trehalose, 0.9mg NaCl and 0.2mg Na2HPO4.

Purification: Immunogen affinity purified.

Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Reference: 1. Bahn, S., Mimmack, M., Ryan, M., Caldwell, M. A., Jauniaux, E., Starkey, M., Svendsen, C. N., Emson, P. Neuronal target genes of the neuron-restrictive silencer factor in neurospheres derived from fetuses with Down's syndrome: a gene expression study. Lancet 359: 310-315, 2002. 2. Okazaki, T., Yoshida, B. N., Avraham, K. B., Wang, H., Wuenschell, C. W., Jenkins, N. A., Copeland, N. G., Anderson, D. J., Mori, N. Molecular diversity of the SCG10/stathmin gene family in the mouse. Genomics 18: 360-373, 1993. Note: Erratum: Genomics 21: 298 only, 1994. 3. Stein, R., Mori, N., Matthews, K., Lo, L.-C., Anderson, D. J. The NGF-inducible SCG10 mRNA encodes a novel membrane-bound protein present in growth cones and abundant in developing neurons. Neuron 1: 463-476, 1988.

Uniprot ID: Q93045

Host: Rabbit

Concentration: Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Conjugate:

Cross Reactivity: No cross-reactivity with other proteins.

Isotype: Rabbit IgG

Phospho_site:

Clone Number:

Observed Molecular Weight: 21 kDa

Calculated Molecular Weight: 32193 MW

Gene ID: 11075

Protein Name: Stathmin-2

Gene Full Name: stathmin 2

Synonyms: Protein SCG10; SCG10; SCGN10; SGC10; Stathmin 2; stathmin like 2; STMN2